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Subutex (Buprenorphine Sublingual Tablets) – Opioid Dependence Treatment

Subutex (generic: buprenorphine) is a partial opioid agonist specifically utilized for opioid dependence treatment—particularly during the induction phase—as part of a comprehensive treatment program including counseling and support.Drugs.com+1   buy subutex online 

What Is Subutex & When Is It Used?

Subutex is indicated for opioid addiction (also called opioid use disorder), helping reduce withdrawal and cravings by activating opioid receptors at a lower level than full agonists.Drugs.com+1patient-info.co.uk It is not prescribed for pain relief.Drugs.com Ideal for initiating treatment before transitioning to maintenance options like Suboxone, Bunavail, or Sublocade.Drugs.comVerywell Health

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Dosage & Administration

Induction Phase

• Begin treatment when early withdrawal symptoms are evident.

• Day 1: Typically 8 mg once daily.

• Day 2: Increase to 16 mg once daily, as tolerated.Drugs.com

Maintenance Phase

• Target range: 4–24 mg/day, with 16 mg/day often considered optimal.Drugs.com

• Administered sublingually. Avoid chewing or swallowing to maximize absorption.Drugs.comMedicines.org.ukWebMD

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Warnings & Safety Precautions

Subutex carries significant health and safety considerations that must be highlighted for quality care:

• High Risk of Misuse & Dependency
  Though a partial agonist, prolonged use can lead to dependence or abuse, especially with improper use.Medicines.org.ukDrugs.com

• Severe Respiratory Depression
  Combining with CNS depressants or alcohol can cause life-threatening breathing issues.Drugs.comWebMDRxList

• Liver Monitoring Required
  Pre-existing liver conditions, hepatitis, or alcohol abuse elevate risk; frequent liver function tests are advised.Medicines.org.ukpatient-info.co.uk

• During Pregnancy/Breastfeeding
  Infants may suffer from withdrawal symptoms (neonatal opioid withdrawal); buprenorphine passes into breast milk.Drugs.compatient-info.co.uk

• Avoid Abrupt Discontinuation
  Sudden stopping may trigger withdrawal. A slow taper under supervision is recommended.Drugs.compatient-info.co.uk

• Transportation Safety
  Subutex may impair alertness—avoid driving or operating heavy machinery until fully aware of effects.Drugs.comWebMD

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Common & Serious Side Effects

Subutex’s side effect profile ranges from mild to severe. Under-reporting can have grave consequences:

• Common: nausea, constipation, insomnia, headache, sweating, dizziness.WebMDDrugs.com

• Less Common: anxiety, dental issues, abdominal pain.Drugs.com

• Serious: respiratory depression, liver injury, allergic reactions, serotonin syndrome (when used with serotonergic drugs), adrenal insufficiency, QT prolongation.Drugs.com+1RxList

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Storage & Disposal

• Store tablets at room temperature, away from moisture and heat.Drugs.com

• Keep out of reach of children—even a single dose can be fatal if ingested inadvertently.Drugs.com

• Dispose of unused medicine via drug take-back programs or per local guidelines; flushing is only when explicitly advised.Drugs.com

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